
If your treatment plan includes chemotherapy, you'll get to know some of these drugs, often given in various combinations.
Adriamycin (Doxorubicin)
Administered by:
Given through IV.
Most common side effects:
- Hair loss
- Nausea, vomiting, and diarrhea
- Bone marrow depression (lowering counts)
- Mouth sores
- Discolored urine
- Skin and nail changes
- Sensitivity to the sun
Important Note:
This kind of chemo (anthracycline) may affect your heart muscle. Check with your doctor before exercising and weightlifting.
Asparaginase A-SPARE-a-gin-ase
Administered by:
Given by injection.
Most common side effects:
- Changes in blood clotting
- Fever and chills
- Allergic reaction
- Lethargy, sleepiness and confusion
Bleomycin Blee-oh-MY-sin (Blenoxane)
Administered by:
Given through IV or injection.
Most common side effects:
- Fever and chills
- Skin and nail changes
- Loss of appetite
- Nausea and vomiting
- Changes to the lungs
Busulfan Byoo-SUL-fan (Myleran)
Administered by:
Given through IV or taken by mouth.
Most common side effects:
- Bone marrow depression (lowering counts)
- Nausea, vomiting, and diarrhea
- Hair loss
- Mouth sores
- Seizures
- Skin changes
Carboplatin KAR-bo-plat-in (Paraplatin)
Administered by:
Given through IV.
Most common side effects:
- Bone marrow depression (lowering counts)
- Nausea and vomiting
- Poor appetite
- May affect your kidneys
- Will lower your pH ct.
- Hearing loss
Carmustine kar-MUS-teen (BCNU)
Administered by:
Given through IV.
Most common side effects:
- Nausea and vomiting
- Bone marrow depression (lowering counts)
- Changes to the skin
Cis-Platinum siss-PLAT-in (Cisplatin)
Administered by:
Given through IV.
Most common side effects:
- Nausea and vomiting (may get worse after a few days)
- Your kidneys may be affected
- Changes to your skin
- Hearing loss
- May cause numbness or tingling in hands or feet
Important Note:
Drink lots of fluid while on this drug. Keep anti-nausea meds nearby!
Cyclophosphamide Sye-kloe-FOSS-fa-mide (Cytoxan)
Administered by:
Given through IV or taken by mouth.
Most common side effects:
- Bone marrow depression (lowering counts)
- Hair loss
- Bladder irritation
- Nausea and vomiting
- Poor of appetite
Cytarabine Sye-TARE-a-been (ARA-C; Cytosar)
Administered by:
Given by injection, IV or intrathecal (injected into fluid around spinal cord).
Most common side effects:
- Bone marrow depression (lowering counts)
- Nausea / vomiting /diarrhea
- Eye irritation
- Mouth sores
- Rash
- A flu-like effect
Daunorubicin Daw-noe-ROO-bi-sun (Daunomycin)
Administered by:
Given through IV.
Most common side effects:
- Nausea and vomiting.
- Hair loss
- Bone marrow depression (lowering counts)
- Mouth sores
- Discolored urine
Important Note:
This kind of chemo (anthracycline) may affect your heart muscle. Check with your doctor before exercising or weightlifting.
Etoposide E-TOE-poe-side (VP-16)
Administered by:
Given through IV or taken by mouth.
Most common side effects:
- Bone marrow depression (lowering counts)
- Hair loss
- Nausea and vomiting, and diarrhea
- Temporary taste alterations
- Mouth sores
- Skin changes
5-Flourouracil floor-oh-YOOR-a-sill (5-FU)
Administered by:
Given through IV or taken by mouth.
Most common side effects:
- Mouth sores
- Diarrhea
- Eye sensitivity
- Skin changes
- Bone marrow depression (lowering counts)
- Nausea and vomiting
- Hair loss
- Sensitivity of the skin to sunlight.
- Rashes
Hydroxyurea Hye-DROX-ee-yoo-REE-ah (Hydrea)
Administered by:
Taken by mouth.
Most common side effects:
- Bone marrow depression (lowering counts)
- Skin changes
Ifosphamide Eye-FOSS-fah-mide (Ifex)
Administered by:
Given through IV.
Most common side effects:
- Bone marrow depression (lowering counts)
- Nausea and vomiting
- Hair loss
- Irritation of the bladder
- Changes to nails
Lomustine Loe-MUS-teen (CCNU; CeeNu)
Administered by:
Taken by mouth.
Most common side effects:
- Nausea and vomiting
- Bone marrow depression (lowering counts)
- Mouth sores
Melphalan MEL-fa-lan (Alkeran)
Administered by:
Given through IV or taken by mouth.
Most common side effects:
- Bone marrow depression (lowering counts)
- Nausea and vomiting
- Mouth sores
- Diarrhea
- Hair loss
- Skin changes
Mercaptopurine Mer-kap-toe-PYOOR-een (Purinethol)
Administered by:
Taken by mouth.
Most common side effects:
- Bone marrow depression (lowering counts)
- Mouth sores
- Skin changes
Methotrexate Meth-o-TREX-ate (Mexate)
Administered by:
Given by mouth, injection, IV or intrathecal (injected into fluid around spinal cord).
Most common side effects:
- Bone marrow depression (lowering counts)
- Mouth sores
- Diarrhea, nausea, vomiting
- Skin changes, rash, hair loss
Paclitaxel PACK-lih-tax-el (Taxol®)
Administered by:
Given through IV.
Most common side effects:
- Bone marrow depression (lowering counts)
- Mouth sores
- Diarrhea, nausea, vomiting
- Hair loss
- Aching or pain in joints and muscles (usually after 2-3 days.
- Gets better within 5-7 days)
- Skin changes
- Numbness or tingling in hands or feet
- Allergic reaction
Procarbazine Pro-KAR-ba-zeen (Matulane; Natulan)
Administered by:
Given through IV or taken by mouth.
Most common side effects:
- Bone marrow depression (lowering counts)
- Nausea and vomiting
- Alcohol should be avoided while taking this drug
6-Thioguanine Six-thigh-oh-GWAN-neen (6-TG)
Administered by:
Taken by mouth.
Most common side effects:
- Bone marrow depression (lowering counts)
- Raised levels of uric acid in the blood
- Skin changes
- Mouth sores
Vinblastine Vin-BLAS-teen (Velban)
Administered by:
Given through IV.
Most common side effects:
- Bone marrow depression (lowering counts)
- Nausea, vomiting, and diarrhea
- Hair loss
- Mouth sores
- Constipation
- Numbness or tingling in hands or feet
Vincristine Vin-KRIS-teen (Oncovin; VCR)
Administered by:
Given through IV.
Most common side effects:
- Abdominal cramps and constipation
- Numbness or tingling in hands or feet
- Jaw pain
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